El diagnóstico de la infección por el virus de la hepatitis C en España: una oportunidad para mejorar
| Autor: | Antonio Aguilera Guirao, Antonio Javier Blasco Bravo, J. María Eiros Bouza, José Luis Calleja Panero, Javier García-Samaniego Rey, Pablo Lázaro y De Mercado, Federico García, Javier Crespo García |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Response rate (survey) medicine.medical_specialty biology business.industry Hepatitis C virus 030106 microbiology Single sample Hepatitis C medicine.disease medicine.disease_cause Virus 03 medical and health sciences 0302 clinical medicine Internal medicine Genotype biology.protein medicine 030212 general & internal medicine Antibody business Viral load |
| Zdroj: | Enfermedades Infecciosas y Microbiología Clínica. 37:231-238 |
| ISSN: | 0213-005X |
| DOI: | 10.1016/j.eimc.2018.05.016 |
| Popis: | Background Reflex testing of antibodies and viral load in the same sample for diagnosing hepatitis C virus infection speeds up access to treatment. However, how hepatitis C is diagnosed in Spanish hospitals is unknown. Objective To describe the available resources and procedures for the diagnosis of hepatitis C virus infection in Spain. Methods Survey sent to public and private Spanish hospitals with teaching accreditation with at least 200 beds. Results Of the 160 hospitals that met the inclusion criteria, 90 centres (response rate 56.3%) completed the survey. Two hospitals (2.2%) have no diagnostic resources, 15 (16.7%) can only test for anti-hepatitis C virus(Ab), 9 (10.0%) for Ab and viral load, 47 (52.2%) for Ab, viral load and genotype, 2 (2.2%) for Ab, viral load and core antigen, and 15 (16.7%) can perform Ab, core antigen, viral load and genotype tests. When an Ab test is positive, 28 (31.1%) hospitals perform reflex testing. When an active infection is diagnosed, some communication strategy is used in 62 (68.9%) hospitals. Approximately 44.2% of the respondents believe that all determinations needed to reach a definitive diagnosis should be done on a single blood sample. Conclusion Although 81% of Spanish hospitals have the resources to perform reflex hepatitis C virus infection testing, it is only done in 31%, and less than a half of respondents believe that the definitive diagnosis should be performed on a single sample. |
| Databáze: | OpenAIRE |
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