EFFECT OF HEPTRAL ON THE COGNITIVE FUNCTIONS OF RATS AFTER CHRONIC 153 ALCOHOL INTOXICATION

Autor:	Lyudmila E. Borodkina, Yulia A. Smolnyakova, Elena A. Muzyko, Yakov V. Tivon, Ivan N. Tyurenkov
Rok vydání:	2022
Zdroj:	Journal of Volgograd State Medical University. 19:153-157
ISSN:	1994-9499 1994-9480
DOI:	10.19163/1994-9480-2022-19-1-153-157
Popis:	The aim of this study was assess the effect of the heptral on the cognitive functions of female rats exposed to chronic alcohol intoxication (CAI). CAI was modeled with 6-month replacement of drinking water with a 10% solution of ethyl alcohol with sucrose (50 g/l). The "One-way step-down inhibitory (“passive”) avoidance test", "Extrapolation escape task test", "Novel object recognition test" and "Barnes maze test" were carried out at the age of 16 months. The experimental data obtained indicate that there is impairment in preservation of the memory track in female rats after CAI. Heptral neutralized cognitive impairment in animals exposed to prolonged alcohol abuse.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5e312ca2a03be2547cba5d2afa8c46c4 https://doi.org/10.19163/1994-9480-2022-19-1-153-157 Zobrazit plný text záznamu