Spirostanol Saponins from the Fibrous Roots ofOphiopogon japonicus(Thunb.) Ker-Gawl
| Autor: | Chang-Ling Duan, Jian-Xun Liu, Peng Li, Yong Jiang, Peng-Fei Tu, Yu-Juan Li |
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| Rok vydání: | 2010 |
| Předmět: |
biology
Chemistry Stereochemistry Chemical structure Plant composition Organic Chemistry Fibrous root system Ophiopogon japonicus biology.organism_classification Mass spectrometry Biochemistry Catalysis Inorganic Chemistry HeLa Drug Discovery Physical and Theoretical Chemistry Cytotoxicity Chemical composition |
| Zdroj: | Helvetica Chimica Acta. 93:227-232 |
| ISSN: | 1522-2675 0018-019X |
| DOI: | 10.1002/hlca.200900165 |
| Popis: | Three new steroidal saponins, (25R)-ruscogenin-3-yl α-L-rhamnopyranosyl-(12)-[β-D-xylopyranosyl-(14)]-β-D-glucopyranoside (1), diosgenin-3-yl 2-O-acetyl-α-L-rhamnopyranosyl-(12)-[β-D-xylopyranosyl-(14)]-β-D-glucopyranoside (2), and pennogenin-3-yl 2-O-acetyl-α-L-rhamnopyranosyl-(12)-[β-D-xylopyranosyl-(14)]-β-D-glucopyranoside (3) were isolated from the fibrous roots of Ophiopogon japonicus (Thunb.) Ker-Gawl. Their structures were determined by spectroscopic methods including IR, HR-ESI-MS, and 1D- and 2D-NMR. All of these three steroidal saponins exhibited weak cytotoxicities against Hela and Hep2 cell lines. |
| Databáze: | OpenAIRE |
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