| Autor: |
W. S. Blaner, A. Sykes, R. Piantedosi, Silke Vogel |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
Retinoids ISBN: 9783642636141 |
| DOI: |
10.1007/978-3-642-58483-1_4 |
| Popis: |
It is well known from the early literature that liver alcohol dehydrogenase catalyzes the oxidation of retinol to retinal (Blaner and Olson 1994). Similarly, it was established from early work that several members of the aldehyde dehydrogenase family of enzymes are able to catalyze irreversibly the oxidation of retinal to retinoic acid (Blaner and Olson 1994). Thus,it has long been understood that retinoic acid synthesis from its precursor retinol involves a two step oxidation that resembles the oxidation of ethanol to acetic acid. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
