New chiral NiII complexes of Schiff’s bases of glycine and alanine for efficient asymmetric synthesis of α-amino acids

Autor:	A. S. Saghiyan, Victor N. Khrustalev, Arpine V. Geolchanyan, Satenik G. Petrosyan, Luisa L. Manasyan, Silva M. Djamgaryan, Victor I. Maleev, Sargis A. Andreasyan, Slavik A. Dadayan
Rok vydání:	2006
Předmět:	Inorganic Chemistry Alanine chemistry.chemical_classification Base (chemistry) chemistry Stereochemistry Organic Chemistry Glycine Enantioselective synthesis Aldol condensation Physical and Theoretical Chemistry Catalysis Amino acid
Zdroj:	Tetrahedron: Asymmetry. 17:455-467
ISSN:	0957-4166
DOI:	10.1016/j.tetasy.2006.01.026
Popis:	New modified chiral auxiliaries (S)-N-(2-benzoylphenyl)-1-(2-chlorobenzyl)pyrrolidine-2-carboxamide (2-CBPB) and (S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide (3,4-DMBPB) and their NiII complexes of Schiff’s base with glycine and alanine have been synthesized and tested in asymmetric C-alkylation and aldol condensation reactions of amino acid moieties. The tests proved that both new auxiliaries were efficient with the ee’s of the final amino acids as high as 98% even in case of α-methyl-α-amino acid synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5b0a11b93747e31042fffbd1b254e99f https://doi.org/10.1016/j.tetasy.2006.01.026 Zobrazit plný text záznamu Full Text from ScienceDirect