1,1-Dioxothiomorpholines with asymmetric environments: protecting group directed diastereoselectivity of glyco divinyl sulfone cyclization

Autor:	Tarun Kumar Pal, Atanu Bhaumik, Tanmaya Pathak
Rok vydání:	2015
Předmět:	chemistry.chemical_compound chemistry General Chemical Engineering Intramolecular force Organic chemistry Amine gas treating General Chemistry Vinyl sulfone Protecting group Divinyl sulfone Derivative (chemistry)
Zdroj:	RSC Advances. 5:27706-27710
ISSN:	2046-2069
Popis:	Divinyl sulfones derived from pyranoside skeletons afforded 1,1-dioxothiomorpholine with predefined asymmetric environments. Although the exocyclic vinyl sulfone group easily reacts with primary amines, the intramolecular addition pattern of the secondary amine leading to the formation of the 1,1-dioxothiomorpholine derivative dramatically varied when benzylidene protection was replaced by benzyl protecting groups.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5aaf6d01f7040c1600f440036b8674cc https://doi.org/10.1039/c5ra03276h Zobrazit plný text záznamu