Substrate-derived Sortase A Inhibitors: Targeting an Essential Virulence Factor of Gram-positive Pathogenic Bacteria

Autor: Helal Abujubara, Jordi C. J. Hintzen, Shadi Rahimi, Ivan Mijakovic, Daniel Tietze, Alesia A. Tietze
Rok vydání: 2023
Předmět:
Zdroj: Chemical Science.
ISSN: 2041-6539
2041-6520
Popis: The bacterial transpeptidase Sortase A (SrtA) is a surface enzyme of gram-positive pathogenic bacteria. It has been shown to be an essential virulence factor for the establishment of various bacterial...
Databáze: OpenAIRE