Determination of Artemisinin and Moisture Content of Artemisia Annua L. Dry Powder Using a Hand-Held near Infrared Spectroscopy Device

Autor:	X. Simonnet, Mélanie Quennoz, Marine Toussirot, Cédric Camps
Rok vydání:	2011
Předmět:	Chromatography biology Chemistry Near-infrared spectroscopy Hand held Artemisia annua Calibration set Analytical chemistry biology.organism_classification Dry powder Partial least squares regression medicine Artemisinin Water content Spectroscopy medicine.drug
Zdroj:	Journal of Near Infrared Spectroscopy. 19:191-198
ISSN:	1751-6552 0967-0335
Popis:	A rapid, low-cost method, based on near-infrared spectroscopy (NIR), was developed to determine artemisinin and moisture content in dry powder of Artemisia annua (A. annua) leaves. A calibration set of 60 samples and validation set of 40 samples of A. annua hybrids exhibiting artemisinin content of between 0.7% and 1.6% was used. Results of partial least squares modelling indicated that NIR was accurate in predicting artemisinin content. Root mean square error values of cross-validation ( RMSECV) and prediction ( RMSEV) of 0.1% were calculated, in both cases. A model of moisture content was particularly accurate with RMSECV and RMSEP values of 0.8% ( R=0.99) and 1.4%, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::59f545399222ff97ae923b8c924ae685 https://doi.org/10.1255/jnirs.927 Zobrazit plný text záznamu