The Effect of COVID-19 on Long-Term Cardiac Function in Patients With Chronic Heart Failure
| Autor: | A. A. Ageev, M. V. Kozhevnikova, A. V. Emelyanov, A. V. Krivova, Yu. F. Shumskaya, L. M. Musaeva, L. V. Popova, Yu. I. Naymann, G. B. Abdullaeva, E. V. Privalova, Yu. N. Belenkov |
|---|---|
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Kardiologiia. 62:23-29 |
| ISSN: | 2412-5660 0022-9040 |
| DOI: | 10.18087/cardio.2022.12.n2265 |
| Popis: | Aim To evaluate functional changes in the heart in the long-term following COVID-19 in patients with chronic heart failure (CHF).Material and methods Case reports of 54 patients aged 69.1±9.7 years who had COVID-19 from January 2021 through January 2022 and had been previously diagnosed with NYHA functional class II-III CHF were studied. Two comparison groups were isolated: HF with LV EF >50 % (n=39) and Results In all CHF patients after COVID-19 at 5.8 months on average, LV EF decreased (median difference, 2.5 %; 95 % confidence interval (CI): 6.99×10–5– 4.99) and PASP increased (median difference, 8 mm Hg; 95 % CI: 4.5–12.9). In the HF group with LV EF 50 % (6.9 and 0.7 %, respectively; p=0.037); furthermore, the CHF phenotype did not influence the change in PASP (p=0.4). The one-factor regression analysis showed that the dynamics of LV EF decrease was significantly influenced by the baseline decrease in LV EF, whereas the change in PASP was influenced by the dynamics of LV EF decrease, presence of dyslipidemia, and statin treatment. Furthermore, the multifactorial analysis showed that prognostically significant factors for long-term changes in LV EF following COVID-19 were male gender (odds ratio (OR), 5.92; 95 % CI: 1.31–26.75; p=0.014), LV EF at baseline Conclusion This study showed that COVID-19 in the long term can influence the course of CHF; in this process, HF patients with EF 50 % have an isolated increase in PASP. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|