Endoscopic Criteria for Invasive Depth of Superficial Esophageal Cancer

Autor: Hiroyasu Makuuchi, Takao Machimura, Toshio Mitomi, Kyoichi Mizutani, Takayuki Nishi, Yoshifumi Kise, Osamu Chino, Hideo Shimada, Yoshiyuki Osamura, Hikaru Tanaka, Takeshi Miwa
Rok vydání: 1997
Předmět:
Zdroj: Digestive Endoscopy. 9:110-115
ISSN: 1443-1661
0915-5635
Popis: The therapeutic strategy for superficial esophageal cancer should be determined by the depth of invasion. Therefore, we endeavored to develop reliable criteria for endoscopic evaluation of the invasive depth of superficial esophageal cancer. Two hundred and fifty nine superficial squamous cell carcinoma cases were enrolled in this study, designed to investigate the relationship between endoscopic classification and the depth of invasion, and also between lesion size and depth of invasion. Almost all 0-1, 0-1+0-llc, O-llc+0-lla and 0-111 lesions invaded the submucosal layer, although 0-lla and O-llb lesions were limited to the mucosal layer. The 0-llc type of lesion showed a wide range of invasive depths from M1 to SM3; in M1 cases with minimal depression the surface appears entirely smooth; in M2 cases the depressed surface is uniformly granular; and M3 cases have slightly larger granules. With submucosal cancer, the depressed surface showed some irregularity and variability in granule size. In the 0-llc type, 100% of lesions under 10 mm and 80% of those under 30 mm in greatest dimension were mucosal cancer. The accuracy of our criteria for endo-scopically evaluating the depth of invasion was 80.2%. The accuracy rate, in terms of assignment to group Ml and M2, M3 and SM1, or SM2 and SM3, was 90.6%.
Databáze: OpenAIRE