Neo-adjuvant infusion Cisplatin, 5-FU and high-dose leucovorin for squamous cell carcinoma of the head and neck (SCCHN): high rates of complete response (CR) and definitive radiotherapy as primary site management

Autor:	Paul M. Busse, Emil Frei, D. Casey, C. M. Norris, J. Lucarini, Janet Andersen, Renee M. Rossi, Arnon I. Dreyfuss, Jeffrey W. Clark
Rok vydání:	1994
Předmět:	Cisplatin High rate Oncology Chemotherapy medicine.medical_specialty business.industry medicine.medical_treatment Neo adjuvant law.invention Randomized controlled trial law Internal medicine Medicine business Site management Definitive radiotherapy Complete response medicine.drug
Zdroj:	Cancer Treatment An Update ISBN: 9782817807676
Popis:	The role of Neo-Adjuvant chemotherapy for patients with advanced SCCHN remains controversial. While results from randomized trials of Neo-Adjuvant therapy have confirmed an association between response and treatment outcome, an improvement in survival has not been reported. Critical review of latter studies however, reveals flaws which limit the value of their findings [1]. An improvement in the survival of patients who receive Neo-Adjuvant therapy for SCCHN may not be confirmed until the rate of CR is consistently over 50 % and local-regional treatment is optimal [1].
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5820b1d79c5b4fb989052bde01ef1be7 https://doi.org/10.1007/978-2-8178-0765-2_37 Zobrazit plný text záznamu