Mild cognitive impairment diagnosed with the new DSM-5 criteria: prevalence and associations with non-cognitive psychopathology
| Autor: | Antonio Lobo, Pedro Saz, Leocadio Rodríguez-Mañas, Elena Lobo, Michael E. Dewey, Pedro J. Modrego, Guillermo Marcos, Patricia Gracia-García, Javier Santabárbara, Josep Maria Haro, G. Pirez, Raúl López-Antón, Concepción De-la-Cámara |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
education.field_of_study Population Logistic regression behavioral disciplines and activities nervous system diseases DSM-5 Psychiatry and Mental health mental disorders Epidemiology medicine Anxiety medicine.symptom Psychology Psychiatry Cognitive impairment education human activities Depression (differential diagnoses) Clinical psychology Psychopathology |
| Zdroj: | Acta Psychiatrica Scandinavica. 131:29-39 |
| ISSN: | 0001-690X |
| Popis: | Objective To contrast the prevalence of mild cognitive impairment (MCI) as diagnosed using DSM-5 criteria (DSM5-MCI) with MCI as diagnosed using Petersen's criteria (P-MCI) and to explore the association of both with non-cognitive psychopathological symptoms (NCPS). Method A two-phase epidemiological screening was implemented in a population-based sample of individuals aged 55+ (n = 4803). The Geriatric Mental State (GMS) was the main psychopathological instrument used, and AGECAT was used to make psychiatric diagnoses. Research psychiatrists diagnosed DSM5-MCI and P-MCI using operational criteria. Logistic regression models were then used to investigate the association of MCI with anxiety and depression and with NCPS. Results Weighted prevalence of DSM5-MCI and P-MCI was, respectively, 3.72% and 7.93% for the aged 65+. NCPS were common in both MCI categories, but negative-type symptoms such as ‘anergia’ and ‘observed slowness’ were considerably more frequent among persons with DSM5-MCI. Anxiety and depression diagnostic categories were associated with both P-MCI and DSM5-MCI, but affective-type symptoms were mainly associated with P-MCI. Some negative-type symptoms were inversely associated with P-MCI, and no association was observed with DSM5-MCI. Conclusion The prevalence of DSM5-MCI was half that of P-MCI. Negative-type NCPS were more frequently and typically associated with DSM5-MCI. |
| Databáze: | OpenAIRE |
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