Hydrogenolysis of the C-O bond of hydroxylactams as a convenient method for the synthesis of substituted isoindolin-1-ones
Autor: | Maxim G. Vinogradov, E. V. Starodubtseva, O. V. Turova, Zh. R. Sagirova |
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Rok vydání: | 2013 |
Předmět: | |
Zdroj: | Russian Chemical Bulletin. 62:1032-1037 |
ISSN: | 1573-9171 1066-5285 |
DOI: | 10.1007/s11172-013-0137-7 |
Popis: | A simple and efficient method for the synthesis of isoindolin-1-ones containing alkyl or aryl substituents at positions 2 and (or) 3 was suggested. The method is based on the earlier unknown Pd0-catalyzed hydrogenolysis of hydroxylactams. |
Databáze: | OpenAIRE |
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