Hydrogenolysis of the C-O bond of hydroxylactams as a convenient method for the synthesis of substituted isoindolin-1-ones

Autor: Maxim G. Vinogradov, E. V. Starodubtseva, O. V. Turova, Zh. R. Sagirova
Rok vydání: 2013
Předmět:
Zdroj: Russian Chemical Bulletin. 62:1032-1037
ISSN: 1573-9171
1066-5285
DOI: 10.1007/s11172-013-0137-7
Popis: A simple and efficient method for the synthesis of isoindolin-1-ones containing alkyl or aryl substituents at positions 2 and (or) 3 was suggested. The method is based on the earlier unknown Pd0-catalyzed hydrogenolysis of hydroxylactams.
Databáze: OpenAIRE