Posterior urethral valves and vesicoureteral reflux: can prenatal ultrasonography distinguish between these two conditions in male fetuses?
| Autor: | Annabel Paye-Jaouen, Christine Grapin-Dagorno, Diane Korb, Thomas Schmitz, Jean-François Oury, Yvon Chitrit, Mathilde Bourdon, Félicia Joinau-Zoulovits, Matthieu Peycelon, Alaa El Ghoneimi, Edith Vuillard, Nadia Belarbi, Anne-Lyse Delezoide, Olivier Sibony |
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| Rok vydání: | 2016 |
| Předmět: |
Pregnancy
medicine.medical_specialty Fetus 030219 obstetrics & reproductive medicine business.industry 030232 urology & nephrology Urology Obstetrics and Gynecology urologic and male genital diseases medicine.disease Vesicoureteral reflux female genital diseases and pregnancy complications 03 medical and health sciences Urethral Diseases 0302 clinical medicine Urethra medicine.anatomical_structure Ureter Medicine business Urethral valve Renal pelvis Genetics (clinical) |
| Zdroj: | Prenatal Diagnosis. 36:831-837 |
| ISSN: | 0197-3851 |
| DOI: | 10.1002/pd.4868 |
| Popis: | Objective To evaluate prenatal sonographic signs that distinguish male fetuses with posterior urethral valves (PUV) from those with vesicoureteral reflux (VUR). Methods Antenatal data were retrospectively retrieved from all consecutive women delivering between 2003 and 2012 of a male newborn with a postnatal diagnosis of PUV or VUR. Prenatal parameters included fetal bladder characteristics, identification of a dilated posterior urethra, and change in shape and size in the fetal renal pelvis or ureter. Results 136 women gave birth to a male newborn with a postnatal diagnosis of PUV (n = 49) or VUR (n = 87). The presence of posterior urethral dilatation (21 [42.9%] fetuses versus 0 [0%], p = 0.000), a thickened fetal bladder wall (37 [75.5%] versus 4 [4.6%], p = 0.000) and anhydramnios (14 [28.6%] versus 0, p = 0.000) were strongly associated with the postnatal diagnosis of PUV. Change in shape and size in the fetal renal pelvis or ureter was observed in 15 (17.2%) of 87 children with VUR versus 1 (2.0%) out of 49 with PUV (p = 0.010). Conclusions Prenatal ultrasound may differentiate with reasonable accuracy male fetuses with a postnatal diagnosis of PUV from those with VUR. |
| Databáze: | OpenAIRE |
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