Synthesis, characterization and biomedical activities of molybdenum complexes of tridentate Schiff base ligands. Crystal and molecular structure of [MoO2(L10)(DMSO)] and [MoO2(L11)(DMSO)]
| Autor: | Sukla Rakshit, Tapashi G. Roy, Debashis Palit, Dieter Rehder, Saroj K. S. Hazari, Falk Olbrich, Saswata Rabi |
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| Rok vydání: | 2016 |
| Předmět: |
Antifungal
Schiff base 010405 organic chemistry medicine.drug_class Stereochemistry chemistry.chemical_element 010402 general chemistry 01 natural sciences 0104 chemical sciences Inorganic Chemistry Crystal chemistry.chemical_compound chemistry Molybdenum X-ray crystallography Polymer chemistry Materials Chemistry medicine Proton NMR Molecule Physical and Theoretical Chemistry Antibacterial agent |
| Zdroj: | Polyhedron. 117:224-230 |
| ISSN: | 0277-5387 |
| Popis: | The molybdenum complexes of different Schiff base ligands have drawn remarkable attention due to their different biological and analytical activities. Several molybdenum complexes of different Schiff base ligands, L1 to L11 derived from dithiocarbazate, have been synthesized by the reaction of the ligands with molybdenum(VI)acetylacetonate. The complexes were characterized on the basis of IR, 1H NMR and electronic spectral analyses, along with elemental, magnetochemical and conductometric data. All the complexes are diamagnetic and non-electrolytes in DMF solution. The molecular structures of two complexes were confirmed by X-ray crystallographic studies. Antibacterial and antifungal characteristics of the concerned compounds were investigated against different gram-positive and Gram negative bacteria, and against fungi, respectively. Most of the complexes show good activity against fungi and bacteria; in some cases, the complexes were more active than the standard medications Nystatin and Ampicillin respectively. |
| Databáze: | OpenAIRE |
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