Prospective clinical applications of nanosized drugs

Autor:	V. Yu. Balaban’yan, D. L. Shobolov, V. I. Shvets, Yu. M. Krasnopol’skii
Rok vydání:	2013
Předmět:	Liposome medicine.anatomical_structure Membrane Solubilization Chemistry Cell Toxicity Drug delivery medicine General Chemistry Mononuclear phagocyte system Pharmacology Blood–brain barrier
Zdroj:	Russian Journal of General Chemistry. 83:2524-2540
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363213120517
Popis:	Liposomes reduce toxicity of their encapsulated APIs. They allow drugs to penetrate cell membranes, serve as containers for drug delivery, protect drugs from enzymatic degradation, provide prolonged action due to slow drug release, and protect drugs from the reticuloendothelial system. Liposomeencapsulated drugs break through the blood brain barrier. Liposomes can solubilize water-insoluble drugs [54, 55, 58, 76, 77, 82].
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::55c66f4dd1dc24d91574fad60cf1859f https://doi.org/10.1134/s1070363213120517 Zobrazit plný text záznamu Plný text ve formátu PDF