| Autor: |
G. M. Divert, S. G. Krivoshchekov, V. E. Divert |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
Human Physiology. 30:330-335 |
| ISSN: |
0362-1197 |
| DOI: |
10.1023/b:hump.0000029182.93218.3b |
| Popis: |
A study was made of the effects of a 20-day course of intermittent normobaric hypoxia (INH) on the parameters of gas exchange and the regulation of respiration in healthy volunteers. A phasic change in oxygen consumption at rest was observed: it decreased on the 10th day of the INH course and increased on the 20th day, with a parallel increase in the efficiency of pulmonary ventilation. According to the hypercapnic test, the ventilatory response threshold decreased, whereas ventilatory sensitivity increased; these effects were most pronounced during the first ten days of INH training and still detectable in recovery. It was assumed that the first phase of training (up to the tenth day) is associated with compensatory activation of pulmonary ventilation owing to an increase in peripheral and central chemosensitivity to the CO2 stimulus. In the second phase, which was associated with further slight changes in the parameters of external respiration, the gas exchange level is restored owing to an adaptive increase in efficiency of oxygen utilization in cells and tissues. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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