Urine Tenofovir Levels Strongly Correlate With Virologic Suppression in Patients With Human Immunodeficiency Virus on Tenofovir Alafenamide-Based Antiretroviral Therapy

Autor:	Kelly A Johnson, Hideaki Okochi, Mireya Arreguin, Joseph Watabe, David V Glidden, Anindita Chattopadhyay, Elizabeth Imbert, Matthew D Hickey, Monica Gandhi, Matthew Spinelli
Rok vydání:	2022
Předmět:	Microbiology (medical) Infectious Diseases
Zdroj:	Clinical Infectious Diseases. 76:930-933
ISSN:	1537-6591 1058-4838
DOI:	10.1093/cid/ciac828
Popis:	We found that urine tenofovir (TFV) levels >1500 ng/mL strongly predict virologic suppression among people with human immunodeficiency virus taking tenofovir alafenamide (odds ratio, 5.66; 95% confidence interval, 1.59–20.14; P = .007). This suggests an existing point-of-care assay developed for tenofovir disoproxil fumarate will support adherence monitoring for patients on all TFV-based antiretrovirals.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::54edd8b3281062c06a9b6b849539e637 https://doi.org/10.1093/cid/ciac828 Zobrazit plný text záznamu