Treatment of catastrophic antiphospholipid syndrome to pregnant woman

Autor:	Nataliya Tytarenko, Inna Kukuruza, Olga Zasadn?uk, Andrii Vozniuk, Andriy Kostyuchenko
Rok vydání:	2022
Předmět:	General Nursing Education
Zdroj:	International journal of health sciences. 6:378-387
ISSN:	2550-696X 2550-6978
DOI:	10.53730/ijhs.v6n1.4524
Popis:	The research aimed to study and analyze the life-threatening complication of antiphospholipid syndrome by acute thrombotic microangiopathy, which can lead to multiorgan damage. The progression of catastrophic antiphospholipid syndrome during pregnancy creates a lot of problems in diagnostic due to its extended clinical manifestations and coincidence with additional obstetric intricacies and microangiopathic diseases. Early diagnosis and aggressive treatment (anticoagulants, glucocorticoids, and plasma metabolism (or intravenous immunoglobulins) remain key factors for favorable. In cases of refractory CAPS, cyclophosphamide or monoclonal antibodies (rituximab, eculizumab) should be considered.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::54a40a97eee7e5e7e2b741fe278bd887 https://doi.org/10.53730/ijhs.v6n1.4524 Zobrazit plný text záznamu