Autor: |
Kaori Fujii, Chisa Murakami, Fumio Tsuda, Kiwamu Okita, Masaaki Korenaga, Muneko Okazaki, Makoto Mayumi, Keisuke Hino, Michiari Okuda, Hiroaki Okamoto |
Rok vydání: |
1999 |
Předmět: |
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Zdroj: |
Hepatology Research. 14:204-211 |
ISSN: |
1386-6346 |
DOI: |
10.1016/s1386-6346(99)00002-9 |
Popis: |
It remains controversial if hepatitis C virus (HCV) genotypes in the same genetic group or type are different in the activity of viral replication and capacity to induce severe clinical disease. HCV genotypes and HCV RNA titers were determined in consecutive 264 patients with chronic liver disease in Yamaguchi, Japan. Genotype I/1a was detected in 3 (1%), II/1b in 192 (74%), III/2a in 46 (18%), IV/2b in 17 (6%) and co-infection with II/1b and III/2a in 3 (1%); HCV RNA titers in the remaining three patients were too low to be genotyped. The patients with genotype III/2a were significantly older (P |
Databáze: |
OpenAIRE |
Externí odkaz: |
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