Synthesis of N-Aryl-4-arylhexahydroquinoline Derivatives by Reaction of Cyclic Enaminones with Arylidenemalononitriles in DMSO
Autor: | Tsunaki Onizawa, Wei Han, Takeshi Oriyama, Chika Inoue |
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Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Synthesis. 53:1495-1502 |
ISSN: | 1437-210X 0039-7881 |
Popis: | The reaction of cyclic enaminones with arylidenemalononitriles was carried out in the presence of 13X molecular sieves in dimethyl sulfoxide. Under these mild reaction conditions, various bioactive N-aryl-4-arylhexahydroquinoline derivatives were obtained in high yields without the necessity of using transition-metal catalyst, organobase, or reflux conditions. |
Databáze: | OpenAIRE |
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