A new furostanol glycoside with fatty acid synthase inhibitory activity from Ophiopogon japonicusa
| Autor: | Chang-Ling Duan, Yi Wang, Peng-Fei Tu, Jian-Xun Liu, Xiaofeng Ma, Yong Jiang |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Furostanol glycosides
biology Liliaceae Chemistry Ophiopogon japonicus Fibrous root system Plant Science General Chemistry biology.organism_classification General Biochemistry Genetics and Molecular Biology Fatty acid synthase Ophiopogon Biochemistry biology.protein Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | Chemistry of Natural Compounds. 48:613-615 |
| ISSN: | 1573-8388 0009-3130 |
| DOI: | 10.1007/s10600-012-0325-y |
| Popis: | A new furostanol glycoside, named ophiopogonin J (1), was isolated from the fibrous root of Ophiopogon japonicas. The structure of the compound was established as (25R)-26-[(O-β-D-glucopyranosyl-(1 → 2)-β-D-glucopyranosyl)]-20α -hydroxyfurost-5, 22-diene-3-O-α-L-rhamnopyranosyl-(1 → 2)-[β-D-xylopyranosyl(1 → 4)]-β-D-glucopyranoside on the basis of spectroscopic methods, including HR-ESI-MS and 1D and 2D NMR experiments. |
| Databáze: | OpenAIRE |
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