Chitosan Isolated from Horseshoe Crab Tachypleus gigas from the Malay Peninsula
| Autor: | Wan Nurul Akmal Wan Murni, Mohd Razali Razak, Sakinah Begum Adam, Zaleha Kassim |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Phytochemistry
010504 meteorology & atmospheric sciences biology Chemistry Significant difference General Chemistry 010501 environmental sciences biology.organism_classification 01 natural sciences Biochemistry Horseshoe crab Demineralization Malay peninsula Chitosan chemistry.chemical_compound Drug Discovery Environmental Chemistry Food science Antibacterial activity Tachypleus gigas 0105 earth and related environmental sciences |
| Zdroj: | Oriental Journal of Chemistry. 34:928-933 |
| ISSN: | 2231-5039 0970-020X |
| DOI: | 10.13005/ojc/340242 |
| Popis: | Chitosan that was isolated from horseshoe crabs, Tachypleus gigas, for this study were from estuary area in Balok Pahang (East coast) and Muar Johor (West coast) of the Malay Peninsula. The isolation of chitosan was carried out by chemical processes involving deproteinization, demineralization and deacetylation. Physicochemical properties and antibacterial activity were analysed to determine its potential commercialization. The degree of deacetylation (DD) was higher for samples from Balok than Muar (42.4% and 35.2% respectively), but lesser than the commercial grade. There was no significant difference (p>0.05) in the physicochemical properties but obviously they had lesser moist (1.11±0.22 - 1.25±0.13%), higher ash content (1.99±0.06 - 2.37±0.07%), and low in its solubility (58.00±9.63 - 61.70±1.35%) as well as viscosity (52.52±5.38 - 64.37±4.73 cP) if compared with commercial chitosan. Chitosan from both field sites also showed great antibacterial activities which concentration dependent against Staphylococcus aureus and Eschericia coli. |
| Databáze: | OpenAIRE |
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