Epidemiology and outcome of ventilator associated pneumonia in an tertiary care ICU of India
| Autor: | Arup Basu, Debashish Dhar, Shuvranu Ghosh, Neeraj Goel, Amit Dhamija |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
APACHE II biology business.industry Incidence (epidemiology) Mortality rate Ventilator-associated pneumonia 030208 emergency & critical care medicine Acinetobacter bacterial infections and mycoses biology.organism_classification medicine.disease respiratory tract diseases Acinetobacter baumannii 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Intensive care Internal medicine Epidemiology Medicine business |
| Zdroj: | Respiratory infections. |
| DOI: | 10.1183/13993003.congress-2018.pa4717 |
| Popis: | Introduction: Despite wideprevalence of VAP throughout the intensive care arena and magnanimous work on the field to curb its occurrences , more than 50% of patients diagnosed with VAP do not have the disease whereas up to one-third are not diagnosed. We here aim to profile Indian scenario better on VAP. Aim: The aim of the study is to study the incidence and clinical profile of VAP and to establish the microbiological etiology and their drug sensitivity in patients with VAP. Methodology: This prospective observational study was carried out over a period of 20 months in ICU of a tertiary Care hospital (New Delhi). Patients on ventilator more than 48 hours were evaluated for the presence of VAP by CPIS scoring (cutoff >6). Endotracheal aspirate or bronchoalveolar lavage samples of suspected cases of VAP were collected from ICU patients and processed as per standard protocols. Identification and sensitivity were done by MALDITOF (Biomerieux, France) and VITEK II (Biomerieux, France) automated systems respectively. Results: 84 patients of VAP were identified over the study period. The VAP rates were found to be 6.242/ 1000 ventilator days. Mortality in the VAP patients was 61.84%. Acinetobacter baumannii (37.63%) and Klebsiella pneumoniae (36.55%) was the commonest organism isolated followed by Pseudomonas aeruginosa and Staphylococcus aureus. Majority of them were MDR. Also a significant correlation of high APACHE II and CPIS scores were found with mortality. Conclusion: We found a high prevalence of MDR organism in our study. Most common pathogens were Acinetobacter and Klebsiella. VAP rates in our study was low when compared to other recent Indian data, however mortality rates were high. |
| Databáze: | OpenAIRE |
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