| Autor: |
D. Lopez-Trabada Ataz, S. Lopez-Tarruella Cobo, Y. Jerez Gilarranz, M. Martin Jimenez, E. Ceballos, A.B. Ruperez Blanco, S. Custodio Cabello |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
The Breast. 21:S19 |
| ISSN: |
0960-9776 |
| DOI: |
10.1016/s0960-9776(12)70065-6 |
| Popis: |
undergoing BCT in the Indian scenario hypothesizing that for carefully selected patients BCT is a viable treatment option. Methods: In a retrospective review of prospectively maintained computerized database of 2500 operated breast cancer patients a total of 355 patients undergoing BCT were identified. Patients with age less than 40 years at presentation, unilateral lesion and known receptor and Her 2 status were included. Patients who received NACT and who did not complete planned RT were excluded. Results: 136 patients under 40 years of age had BCT. These patients were divided into TNBC and Non TNBC groups. TNBC patients constituted 54% of patients. Mean age (34.7 vs 35.1), tumour size (3.1 vs 2.6), stage at presentation (Stage I 15% vs 20%, Stage II 65% vs 75%, Stage III 20% vs 5%), pathological nodal status (pN0 53% vs 62%) and average LN dissected (11.5 vs 12.5) were comparable in the two groups. Standard lumpectomy was offered to all patients whereas Quadrantectomy (14% vs 6%) and Oncoplasty with volume replacement (4 patients vs. 2 patients) was used in both groups. At a mean follow up of 36 months Loco regional recurrence was 2.74% vs. 1.6% and Distant metastasis 6.8% vs. 11.1% in TNBC and non-TNBC group respectively. Discussion: Results of the present study indicate feasibility and safety of BCT in young TNBC patients. Hence young age at presentation associated with TNBC is not a contraindication for BCT provided they fulfill the standard criteria for BCT. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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