An efficient method for the chemoselective synthesis of acylals from aromatic aldehydes using bismuth triflate

Autor:	Marc D. Carrigan, Ram S. Mohan, Matthew C. Oswald, Kyle J. Eash
Rok vydání:	2001
Předmět:	Bismuth triflate Acylation Reaction conditions Moisture Chemistry Organic Chemistry Drug Discovery Organic chemistry Biochemistry Catalysis
Zdroj:	Tetrahedron Letters. 42:8133-8135
ISSN:	0040-4039
Popis:	Aromatic aldehydes are smoothly converted into the corresponding acylals in good yields in the presence of 0.10 mol% Bi(OTf)3·xH2O. Ketones are not affected under the reaction conditions. The highly catalytic nature of bismuth triflate and the fact that it is relatively non-toxic, easy to handle and insensitive to small amounts of air and moisture makes this procedure especially attractive for large-scale synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::503813100fac96cb384bbcb60a903d6a https://doi.org/10.1016/s0040-4039(01)01756-7 Zobrazit plný text záznamu Full Text from ScienceDirect