Targeting the pain, inflammation and immune (PII) axis: plausible rationale for LLLT

Autor:	Praveen R. Arany, Snehlata Kulhari, Eason Hahm
Rok vydání:	2012
Předmět:	business.industry Mechanism (biology) medicine.medical_treatment Context (language use) Inflammation Dermatology Disease Bioinformatics Clinical disease Patient acceptance Immune system Immunology Medicine Surgery medicine.symptom business Low level laser therapy
Zdroj:	Photonics & Lasers in Medicine. 1
ISSN:	2193-0643 2193-0635
Popis:	Low-level laser therapy (LLLT) has been used in many clinical contexts. Although its precise mechanism is unclear, its current use is based predominantly on its non-invasive nature and popular patient acceptance. This review attempts to provide a framework for the clinical disease-disorder states focusing on the etiopathology namely; pain, inflammation and immune response termed the PII axis. Following a brief introduction, the literature on the ability of LLLT to modulate the PII axis in specific disease states is reviewed. The triad of critical parameters for LLLT namely, the dose, the biological context and the mechanism are highlighted. This work suggests that LLLT could be a potent primary interventional modality when used to specifically target the PII axis in clinical disease management.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4fbef426361bc74faeb329d20ad559d4 https://doi.org/10.1515/plm-2012-0033 Zobrazit plný text záznamu