Novel quinoline/thiazinan-4-one hybrids; design, synthesis, and molecular docking studies as potential anti-bacterial candidates against MRSA

Autor: Asmaa H. Mohamed, Sara M. Mostafa, Ashraf A. Aly, Alaa A. Hassan, Esraa M. Osman, AbdElAziz A. Nayl, Alan B. Brown, Elshimaa M. N. Abdelhafez
Rok vydání: 2023
Předmět:
Zdroj: RSC Advances. 13:14631-14640
ISSN: 2046-2069
DOI: 10.1039/d3ra01721d
Popis: In an attempt to develop effective and safe antibacterial agents, thiazinanones bearing the quinolone scaffold were prepared by reaction of the corresponding (quinolinylmethylene)hydrazinecarbothioamides with 2,3-diphenylcycloprop-2-enone.
Databáze: OpenAIRE