Novel quinoline/thiazinan-4-one hybrids; design, synthesis, and molecular docking studies as potential anti-bacterial candidates against MRSA
Autor: | Asmaa H. Mohamed, Sara M. Mostafa, Ashraf A. Aly, Alaa A. Hassan, Esraa M. Osman, AbdElAziz A. Nayl, Alan B. Brown, Elshimaa M. N. Abdelhafez |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | RSC Advances. 13:14631-14640 |
ISSN: | 2046-2069 |
DOI: | 10.1039/d3ra01721d |
Popis: | In an attempt to develop effective and safe antibacterial agents, thiazinanones bearing the quinolone scaffold were prepared by reaction of the corresponding (quinolinylmethylene)hydrazinecarbothioamides with 2,3-diphenylcycloprop-2-enone. |
Databáze: | OpenAIRE |
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