Assessment of long-term sequelae of pulmonary dysfunction associated with COVID 19 by using pulmonary pulse transit time

Autor: Mustafa Duran, Turgut Uygun, Ercan Kurtipek
Rok vydání: 2022
DOI: 10.21203/rs.3.rs-1471135/v1
Popis: Purpose: Studies report deleterious impacts of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on multiple organs in the human body, not only in the acute infection period but also in the long-term sequelae. Recently defined pulmonary pulse transit time” (pPTT) was found to be a useful parameter regarding the evaluation of pulmonary hemodynamics. The purpose of this study was to determine whether pPTT might be a favorable tool for detecting the long-term sequelae of pulmonary dysfunction associated with coronavirus disease 2019 (COVID 19).Methods: We evaluated 102 eligible patients with a prior history of laboratory-confirmed COVID 19 hospitalization at least 1 year ago and 100 age and sex-matched healthy controls. All participants’ medical records, clinical, and demographic features were analyzed and underwent detailed 12- lead electrocardiography, echocardiographic assessment, and pulmonary function tests.Results: According to our study, pPTT was positively correlated with forced expiratory volume in the 1st second, peak expiratory flow, and tricuspid annular plane systolic excursion, (r= 0.478; pr= 0.294; p= 0.047, r= 0.314; p= 0.032) as well as negatively correlated with systolic pulmonary artery pressure, (r= -0.328; p= 0.021).Conclusion: Our data indicate pPTT might be a convenient method for early prediction of pulmonary dysfunction among COVID 19 survivors.
Databáze: OpenAIRE