| Autor: |
Vladimir Stojanovic, Pavan Bhargava, Asmaysinh Gharia, Mekhail Anwar, Sidney Buchbinder, Christos Adamopoulos, Panagiotis Zarkos, Ali M. Niknejad |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
IEEE Solid-State Circuits Letters. 4:198-201 |
| ISSN: |
2573-9603 |
| DOI: |
10.1109/lssc.2021.3124234 |
| Popis: |
Label-free miniaturized optical sensors can have a tremendous impact on highly sensitive and scalable point-of-care (PoC) diagnostics by monitoring in real-time molecular interactions without any labels. However, current biophotonic platforms are limited by complex optical and external readout equipment, precluding their use in a PoC setting. In this work, we address this challenge by using a first of its kind fully integrated biosensing electronic–photonic system-on-chip (EPSoC) utilizing microring resonators (MRRs) co-integrated with on-chip electronics in a high volume advanced electronic process. We demonstrate the sensing capabilities of the EPSoC, implemented in GF 45-nm RFSOI, by monitoring real-time binding events of streptavidin molecules, unlocking the door toward true monolithic lab-on-chip (LoC) photonic sensors for PoC applications. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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