Decreased fibrinogen levels are associated with severe intraventricular hemorrhage in very low birth weight (VLBW) infants
| Autor: | John F A Murphy, Eleanor J. Molloy, A Twomey, M. White, L. Mac Keogh, Veronica Donoghue, T. O'Carroll, Beatrice Nolan |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty Respiratory distress business.industry Vlbw infants Hypoxia (medical) medicine.disease Fibrinogen Sepsis Low birth weight Intraventricular hemorrhage Pediatrics Perinatology and Child Health medicine Coagulation testing medicine.symptom business reproductive and urinary physiology medicine.drug |
| Zdroj: | Journal of Neonatal-Perinatal Medicine. 4:133-136 |
| ISSN: | 1934-5798 |
| DOI: | 10.3233/npm-2011-2715 |
| Popis: | Reference ranges for coagulation screens in preterm infants were formulated in the 1980s. Preterm infants are at risk of hypocoagulable states due to hepatic immaturity, hypoxia, respiratory distress syndrome and sepsis. Coagulation profiles of very low birthweight (VLBW) infants were assessed and adverse outcomes recorded. A total of 32 VLBW infants had coagulation studies in the first week of life. Fibrinogen was significantly decreased on the third day of life in infants with severe intraventricular hemorrhage (IVH) compared with those with no or mild IVH. Further research on VLBW coagulation profiles may become easier with the development of point-of-care technology. |
| Databáze: | OpenAIRE |
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