Synthesis of new 1,3-thiazole derivatives from 2(5)-hydroxyalkyl-1,3-thiazole-5(2)-carbaldehydes

Autor:	V. O. Sinenko, S. G. Pil’o, S. R. Slivchuk, G. F. Raenko, Volodymyr Brovarets
Rok vydání:	2016
Předmět:	010405 organic chemistry Acetoacetic ester synthesis Biginelli reaction Isoniazid General Chemistry 010402 general chemistry 01 natural sciences 0104 chemical sciences chemistry.chemical_compound chemistry Urea medicine Organic chemistry Thiazole Phenylhydrazine medicine.drug
Zdroj:	Russian Journal of General Chemistry. 86:1597-1603
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363216070100
Popis:	Reactions of substituted 2-hydroxyalkyl-1,3-thiazole-5-carbaldehydes and 5-hydroxyalkyl-1,3-thiazole-2-carbaldehydes with phenylhydrazine, isoniazid, N-substituted rhodanines were performed as well as Biginelli reaction with acetoacetic ester and urea. As a result, new 1,3-thiazole derivatives were obtained. They are of interest as potential bioactive substances.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4e257b03961842c162f40d26561adbb4 https://doi.org/10.1134/s1070363216070100 Zobrazit plný text záznamu Plný text ve formátu PDF