Hydrophilic Pd-phosphines catalyzed one-pot synthesis of substituted isoquinolines, furopyridines and thienopyridines in aqueous medium

Autor: Ravinder Vadde, Veeranna Guguloth, Narasimha Swamy Thirukovela, Ramesh Balaboina, Suresh Paidakula
Rok vydání: 2019
Předmět:
Zdroj: Tetrahedron Letters. 60:297-299
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2018.12.035
Popis: A first example of simple and efficient hydrophilic Pd-phosphine complexes catalyzed one-pot three-component reaction of ortho-bromo aldehydes, terminal alkynes and ammonium acetate proceeds through the tandem coupling-imination-annulation path for the synthesis of substituted isoquinolines, furopyridines and thienopyridines in good to excellent yields in green aqueous medium at mild temperature was described.
Databáze: OpenAIRE