Indikation und Kontraindikation der β-Blocker zur Glaukombehandlung

Autor:	H. Bleckmann, P. Dorow
Rok vydání:	2008
Předmět:	genetic structures business.industry Chronic glaucoma Significant difference Timolol Ventilatory function General Medicine eye diseases Airway resistance Anesthesia medicine Chronic simple glaucoma Breathing sense organs business Pindolol medicine.drug
Zdroj:	DMW - Deutsche Medizinische Wochenschrift. 109:180-183
ISSN:	1439-4413 0012-0472
DOI:	10.1055/s-2008-1069162
Popis:	Local administration of beta-blockers to the eye has proven effective in the treatment of chronic simple glaucoma. However, varying degrees of impaired ventilation, even to the point of being life-threatening, have been reported. The effect of 1% pindolol and 0.5% timolol eye-drops, twice daily applied locally to the eye, on eyeball pressure and airway resistance was measured in 19 patients with chronic glaucoma. Compared with timolol eye-drops, pindolol had little effect on ventilatory functions, i. e. there was a significant difference between them. But the two preparations had similar effects in lowering eye-ball pressure. The likely explanation of this divergent action is the intrinsic sympathomimetic activity of pindolol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4df14e065c1863e94ad6bbc9768ade2e https://doi.org/10.1055/s-2008-1069162 Zobrazit plný text záznamu