| Autor: |
T. Sakurada, A. R. T. Pupulin, N. A. Lima, N. C. S. Santana, J. B. Borges, S. Lautenschlaugher |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
International Blood Research & Reviews. 3:101-108 |
| ISSN: |
2321-7219 |
| DOI: |
10.9734/ibrr/2015/16929 |
| Popis: |
HIV infection is associated with a progressive loss of T cell functional capacity and reduced responsiveness to antigenic stimuli. Neutrophils are crucial cellular components of the innate immune system. Current study evaluates the functional activity of neutrop hils isolated from HIV/ AIDS patients with similar clinical laboratory parameters differing only in the use of antiretroviral therapy (HAART). Two patients HIV/ AIDS patients, a female and a male, were selected for this study, based on clinical histo ry, general physical examination and laboratory tests. Further, two apparently healthy volunteers of the same age and gender former de control group. Neutrophils isolated from human peripheral blood were placed in contact with the yeast in a proportion of 1:10 leukocytes for 1 hour. PMN Fluorescence was detected in FL1 on a flow cytometer and results were recorded as fluorescence intensity and percentage of positive cells in |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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