INSULIN RESISTANCE (IR) OF PUBERTY IS MEDIATED BY GROWTH HORMONE (OH) AMD NOT BY SEX STEROIDS (SS): STUDIES IN BOYS WITH DELAYED PUBERTY

Autor:	O J Klingensmith, F Papanti, C A Bloch
Rok vydání:	1993
Předmět:	Delayed puberty medicine.medical_specialty Research groups Random assignment business.industry Insulin sensitivity Growth hormone medicine.disease Endocrinology Insulin resistance Internal medicine Pediatrics Perinatology and Child Health medicine medicine.symptom business Testosterone
Zdroj:	Pediatric Research. 33:S87-S87
ISSN:	1530-0447 0031-3998
Popis:	Many factors have been invoked for the cause of pubertal IR, including GH, SS, and increasing adiposity. To determine the respective roles of GH and SS in mediating IR, we studied 24 boys with delayed puberty before and after random assignment to one of 4 research groups: Control (Ctrl), Testosterone (T) Rx, GH Rx, GH + T Rx. We quantitated the insulin sensitivity index (IS) via the mininal model approach. GH was measured Q 20 min from 2000 through 0600 via the Hybritech assay.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4db3df83c1ae729e642d8e4cf8889c4a https://doi.org/10.1203/00006450-199305001-00505 Zobrazit plný text záznamu