Synthesis and anti-inflammatory and antipyretic activity of 2-(1′-hydroxy-4′-isopropenyl-1′-methylcyclohexyl-2′-thio)-methylethanoate
Autor: | N. P. Artemova, E. V. Sirazieva, Liliya E. Nikitina, I. V. Akulina, R. S. Garaev, V. A. Startseva, L. Yu. Dorofeeva |
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Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Pharmaceutical Chemistry Journal. 46:20-22 |
ISSN: | 1573-9031 0091-150X |
DOI: | 10.1007/s11094-012-0727-y |
Popis: | 2-(1′-Hydroxy-4′-isopropenyl-1′-methylcyclohexyl-2′-thio)methylethanoate was synthesized via the reaction of (+)-1,2-limonene oxide with methylmercaptoacetate. The acute toxicity and anti-inflammatory and antipyretic activities of the starting compounds and the synthesized terpene sulfide were investigated. |
Databáze: | OpenAIRE |
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