Synthesis and anti-inflammatory and antipyretic activity of 2-(1′-hydroxy-4′-isopropenyl-1′-methylcyclohexyl-2′-thio)-methylethanoate

Autor: N. P. Artemova, E. V. Sirazieva, Liliya E. Nikitina, I. V. Akulina, R. S. Garaev, V. A. Startseva, L. Yu. Dorofeeva
Rok vydání: 2012
Předmět:
Zdroj: Pharmaceutical Chemistry Journal. 46:20-22
ISSN: 1573-9031
0091-150X
DOI: 10.1007/s11094-012-0727-y
Popis: 2-(1′-Hydroxy-4′-isopropenyl-1′-methylcyclohexyl-2′-thio)methylethanoate was synthesized via the reaction of (+)-1,2-limonene oxide with methylmercaptoacetate. The acute toxicity and anti-inflammatory and antipyretic activities of the starting compounds and the synthesized terpene sulfide were investigated.
Databáze: OpenAIRE