Histopathology of the nervous elements in the heart and the aorta of dogs after intravenous injection of adrenalin and caffeine
| Autor: | E. M. Krokhina |
|---|---|
| Rok vydání: | 1962 |
| Předmět: |
Nervous system
Aorta medicine.medical_specialty business.industry Connective tissue General Medicine medicine.disease_cause General Biochemistry Genetics and Molecular Biology Intracardiac injection chemistry.chemical_compound medicine.anatomical_structure chemistry Anesthesia medicine.artery medicine Histopathology Irritation Caffeine business Pyknosis |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 52:967-971 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00786724 |
| Popis: | Repeated intravenous injections to dogs adrenalin (1: 1000 solution) with caffeine (1% solution) in a dose of 1 ml provoke severe injuries of the intramural nervous system of the heart. These derangements are manifested in progressive destruction of the nerve fibers of all calibers as well as of the sensory nerve endings. Irritation phenomena appearing in some of the nerve cells of the intracardiac ganglia after 2–3 injections, are later replaced by pyknosis if these injections are continued. There was focal interstitial myocarditis, and proliferative connective tissue reaction in the aortic wall. No histopathological changes in the myocardium, nervous elements of the heart or aorta were detected in control animals to which these substances were injected subcutaneously. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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