Meningitis caused by extended-spectrum β-lactamase-producing Escherichia coli in infants in France: a case series

Autor: Gabriel Lignieres, Alexis Rybak, Corinne Levy, André Birgy, Stéphane Bechet, Stéphane Bonacorsi, Robert Cohen, Fouad Madhi
Rok vydání: 2023
Předmět:
Zdroj: JAC-Antimicrobial Resistance. 5
ISSN: 2632-1823
DOI: 10.1093/jacamr/dlad042
Popis: Objectives We report the first case series focusing on clinical and biological characteristics of meningitis caused by ESBL-producing Escherichia coli in infants. Methods Between 2001 and 2020, data on all cases of E. coli meningitis were prospectively collected from a network of 259 paediatric wards and 168 microbiology laboratories in France. We analysed the clinical and biological characteristics, short-term complications and long-term sequelae of ESBL-producing E. coli meningitis cases in patients Results In total, 548 cases of E. coli paediatric meningitis were reported. ESBL-producing E. coli represented 12 (2.2%) cases. We included 10 patients aged Conclusions Meropenem seems to be the treatment of choice for ESBL-producing E. coli meningitis in children and needs to be given as early as possible (
Databáze: OpenAIRE