Stoffwechselprodukte von Mikroorganismen. 175. Mitteilung. Tetracenomycin C
| Autor: | Hans Zähner, Karsten Schröder, Axel Zeeck, Wolfgang Weber, Johannes Siebers |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
medicine.drug_class
Stereochemistry Tetracycline Microorganism Antibiotics 01 natural sciences Biochemistry Microbiology Streptomyces 03 medical and health sciences Genetics medicine Molecular Biology 030304 developmental biology 0303 health sciences biology Strain (chemistry) 010405 organic chemistry Chemistry Biological activity General Medicine biology.organism_classification 3. Good health 0104 chemical sciences Fermentation Bacteria medicine.drug |
| Zdroj: | Archives of Microbiology. 121:111-116 |
| ISSN: | 1432-072X 0302-8933 |
| DOI: | 10.1007/bf00689973 |
| Popis: | Streptomyces glaucescens, strain Tu 49 = ETH 22794, produces hydroxystreptomycin as well as the tetracenomycins, a mixture of several lipophilic antibiotics. The main component and the most active one is tetracenomycin C. Tetracenomycin C has a molecular formula C23H20O11 and is chemically related to tetracyclines and anthracyclinones. The pale yellow antibiotic is active against some gram-positive bacteria, especially against streptomycetes. Gram-negative bacteria and fungi are not inhibited. In considering the differences of biological activity and the functional groups of the molecule, tetracenomycin C is not a member of the tetracycline or anthracyclinone group of antibiotics. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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