Tuning chromatic response, sensitivity, and specificity of polydiacetylene-based sensors
| Autor: | Angie Davina Tjandra, Max Weston, Rona Chandrawati |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
Analyte Materials science Polymers and Plastics Diacetylene Organic Chemistry Bioengineering Nanotechnology 02 engineering and technology Polymer Conjugated system 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound Photopolymer chemistry Sensitivity (control systems) Chromatic scale 0210 nano-technology Polydiacetylenes |
| Zdroj: | Polymer Chemistry. 11:166-183 |
| ISSN: | 1759-9962 1759-9954 |
| DOI: | 10.1039/c9py00949c |
| Popis: | Polydiacetylenes (PDAs) are a class of conjugated polymers with unique optical properties that make them excellent materials for the construction of colorimetric sensors. Self-assembly of amphiphilic diacetylene monomers in solution and photopolymerization of neighboring diacetylene groups yield blue-phase PDAs. PDAs can be functionalized with a wide range of recognition elements, and chemical and biological recognition events, e.g. protein-antibody interaction, nucleic acid hybridization, pH change, can generate a visible blue-to-red chromatic transition of PDA. The color change mechanism remains to be fully elucidated and is analyte dependent, and its understanding is key to optimizing PDA-based sensing systems. In this review, we provide an overview of different methods of tuning the chromatic response, sensitivity, and specificity of PDA-based sensors. It draws conclusions regarding the relationship between these variables, specifically sensitivity and specificity, to guide the future development of PDA sensing systems. |
| Databáze: | OpenAIRE |
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