Asymmetric hydrogenation of isophorone in the presence of (S)-proline: Revival of a 20 years old reaction

Autor:	László Vida, Antal Tungler, Mátyás Fodor
Rok vydání:	2009
Předmět:	chemistry.chemical_classification Chiral auxiliary Ketone Asymmetric hydrogenation Cyclohexanone General Chemistry Catalysis Kinetic resolution Reaction rate chemistry.chemical_compound chemistry Organic chemistry Isophorone
Zdroj:	Catalysis Today. 140:58-63
ISSN:	0920-5861
DOI:	10.1016/j.cattod.2008.07.015
Popis:	The asymmetric hydrogenation of isophorone in the presence of ( S )-proline was reinvestigated in the light of recent papers of Torok et al. and Lambert et al. Beside kinetic resolution of trimethyl cyclohexanone with ( S )-proline, the chemo- and diastereoselective hydrogenation of isophorone is the source of optically active trimethyl cyclohexanone, which was proved by reaction rate, GC, GC–MS measurements and preparative experiments.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::47d752190536df2adee0393410da7e41 https://doi.org/10.1016/j.cattod.2008.07.015 Zobrazit plný text záznamu Full Text from ScienceDirect