PREDICTORS OF HIV INFECTION PROGRESSION BEFORE PRESCRIPTION AND ON ART
| Autor: | N. O. Pryimenko, O. H. Marchenko, T. I. Koval, L. Sizova |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
business.industry Parenteral transmission Human immunodeficiency virus (HIV) Retrospective cohort study medicine.disease medicine.disease_cause Acquired immunodeficiency syndrome (AIDS) Internal medicine medicine Medical prescription Hiv transmission business Body mass index Viral load |
| Zdroj: | Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії. 19:57-62 |
| ISSN: | 2077-1126 2077-1096 |
| DOI: | 10.31718/2077-1096.19.3.57 |
| Popis: | The search for predictors of the progression of HIV infection to the clinical stage IV in patients before prescription and on antiretroviral therapy (ART) is an urgent scientific and practical task. The study aimed to identify predictors of the progression of HIV infection to the clinical stage IV in patients before prescribing and on the background ART based on the determination of clinical and genetic markers. A retrospective cohort study of 181 HIV-infected patients was conducted. For statistical data processing, regression analysis was used. Independent predictors of the progression of HIV infection to clinical stage IV in HIV-infected patients prior to ART were: male (p = 0,037), parenteral HIV transmission (p = 0,004), conclusion experience (p = 0,020), body mass index (BMI) less than 18.5 kg / m2 (p = 0,040), initial viral load (HV) of HIV> 1.0 x 105 copies / ml (p = 0,034), initial level of CD4 + T-lymphocytes |
| Databáze: | OpenAIRE |
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