Preparation and characterization of 6-O-caffeic acid chitosan

Autor:	S T Lu, D J Huang, W P Chen, Y L Zhuang, Z Hu
Rok vydání:	2021
Předmět:	Chitosan History chemistry.chemical_compound Chemistry Caffeic acid Computer Science Applications Education Nuclear chemistry
Zdroj:	Journal of Physics: Conference Series. 1765:012029
ISSN:	1742-6596 1742-6588
DOI:	10.1088/1742-6596/1765/1/012029
Popis:	The modified chitosan retains the excellent properties of chitosan and can broaden its application. In this paper, an approach of protection-deprotection was used to synthesize 6-O-caffeic acid chitosan with chitosan as the raw material. Firstly, the free amino group on the 2-position carbon of chitosan was protected by phthaloylation, and then the -OH of 6-position carbon of chitosan reacted with caffeic acid by ester condensation. Finally, in the presence of hydrazine hydrate, the amino group was deprotected to form 6-O-caffeic acid chitosan. Fourier transform infrared (FTIR) spectroscopy and X-ray diffraction (XRD) characterized the structures of the intermediates and products. The results showed that 6-O-caffeic acid chitosan was successfully obtained. Thermogravimetric analysis indicated that 6-O-caffeic acid chitosan had better thermo-stability than chitosan in nitrogen. This will expand the application of chitosan in vaious fields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::464f913faaacdaaa460e3b7dc5cea966 https://doi.org/10.1088/1742-6596/1765/1/012029 Zobrazit plný text záznamu