| Autor: |
Álvaro Henrique Borges, Vinícius Canavarros Palma, Alex Semenoff-Segundo, Natalino Francisco da Silva, Tereza Aparecida Delle, Vedove Semenoff, Evanice Menezes Marçal Vieira |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Scientific Journal of Dentistry. 2:17-21 |
| ISSN: |
2394-7144 |
| Popis: |
Background: The objective of this paper was to present a methodology for osseointegration in rat mandibles. Materials and Methods: A total of 16 Wistar male rats with 400 g were undergone to anesthesia, and then blunt instruments were used to expose the alveolar inferior nerve. Once the nerve canal was emptied, one implant (2.2 mm × 4 mm) was installed near the mandibular canal. The animals were sacrificed within the experimental period of 15 (n = 8) and 30 (n = 8) days. The histomorphometric analysis included both boneimplant contact and bone area. Results: In a comparison of the variables between 15 and 30 days, there were differences in bone maturation (Student’s parametric test for independent samples - P < 0.05). In addition, the technique was shown to be reproducible and performed at a lower cost compared with histological studies involving other animals. Conclusion: This specific technique of placing implants into the mandibles of rats is a viable alternative in studies of this nature. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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