The Comparison of the Expression of Activation Antigens on Peripheral Blood Mononuclear Cells in Chronic Lymphocytic Leukemia and in Hairy Cell Leukemia
| Autor: | É. Pócsik, R. Mihalik, K. Pálóczi, K. Natonek, J. Demter, B. Kotlán, G. G. Petrányi, M. Benczur |
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| Rok vydání: | 1992 |
| Předmět: |
CD20
biology Chemistry Chronic lymphocytic leukemia Cell Gene rearrangement medicine.disease Peripheral blood mononuclear cell medicine.anatomical_structure immune system diseases hemic and lymphatic diseases medicine Cancer research biology.protein Hairy Cell Hairy cell leukemia Activation antigens |
| Zdroj: | Modern Trends in Human Leukemia IX ISBN: 9783540543602 |
| DOI: | 10.1007/978-3-642-76829-3_8 |
| Popis: | Based on the results of the immuno-phenotypical analysis both B-cell chronic lymphocytic leukemia (B-CLL) and B-cell hairy cell leukemia (B-HCL) appear to be derived from activated lymphocytes [1 –4]. However, CLL-B cells represent an earlier stage of differentiation than the cells of HCL. The data of the gene rearrangement studies also suggest that HCL derives from the clonal expansion of a cell at a later developmental stage than the CLL [5]. |
| Databáze: | OpenAIRE |
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