Synthesis of bicyclic systems containing fused sulfolane and isoxazolidine rings

Autor: A. V. Serebryannikova, V. M. Berestovitskaya, L. V. Lapshina, Vladislav V. Gurzhiy, I. E. Efremova
Rok vydání: 2018
Předmět:
Zdroj: Chemistry of Heterocyclic Compounds. 54:76-82
ISSN: 1573-8353
0009-3122
Popis: A method was developed based on reactions of 2-benzylidene-3-methyl-4-nitro-3-thiolene 1,1-dioxide and its substituted analogs with hydroxylamine and N-methylhydroxylamine for the synthesis of 3-aryl-6а-methyl-6-nitrohexahydrothieno[2,3-d]isoxazole 4,4-dioxides – new representatives of original bicyclic structures combining condensed isoxazolidine and sulfolane rings. The structures of the obtained compounds were established by methods of IR spectroscopy, one-dimensional 1Н and 13С NMR spectroscopy, two-dimensional 1Н–13С HMQC and 1Н–13С HMBC experiments, and X-ray structural analysis.
Databáze: OpenAIRE
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