Efficient synthesis of pentacyclic benzosultam-annulated thiopyranoindoles via domino Knoevenagel / intramolecular hetero-Diels–Alder reactions in water
Autor: | Behzad Jafari, Fahimeh Khademi, Peter Langer, Mostafa Kiamehr |
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Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Chemistry of Heterocyclic Compounds. 56:392-398 |
ISSN: | 1573-8353 0009-3122 |
DOI: | 10.1007/s10593-020-02672-x |
Popis: | A convenient catalyst-free synthesis of hitherto unknown pentacyclic benzosultam-annulated thiopyranoindole derivatives is reported which proceeds via domino Knoevenagel / intramolecular hetero-Diels–Alder reactions of (E)-N-alkyl-2-aryl-N-(2-formylphenyl)ethene-1-sulfonamides with indoline-2-thiones in water. The products were obtained regioselectively in high yields. |
Databáze: | OpenAIRE |
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