Efficient synthesis of pentacyclic benzosultam-annulated thiopyranoindoles via domino Knoevenagel / intramolecular hetero-Diels–Alder reactions in water

Autor: Behzad Jafari, Fahimeh Khademi, Peter Langer, Mostafa Kiamehr
Rok vydání: 2020
Předmět:
Zdroj: Chemistry of Heterocyclic Compounds. 56:392-398
ISSN: 1573-8353
0009-3122
DOI: 10.1007/s10593-020-02672-x
Popis: A convenient catalyst-free synthesis of hitherto unknown pentacyclic benzosultam-annulated thiopyranoindole derivatives is reported which proceeds via domino Knoevenagel / intramolecular hetero-Diels–Alder reactions of (E)-N-alkyl-2-aryl-N-(2-formylphenyl)ethene-1-sulfonamides with indoline-2-thiones in water. The products were obtained regioselectively in high yields.
Databáze: OpenAIRE