Routine double-ovarian-stimulation (DuoStim) in poor responders lacks rationale, evidence, and follow-up

Autor:	Angelo Tocci, David Barad, Krzysztof Łukaszuk, Raoul Orvieto
Rok vydání:	2023
Předmět:	Reproductive Medicine Rehabilitation Obstetrics and Gynecology
Zdroj:	Human Reproduction. 38:329-333
ISSN:	1460-2350 0268-1161
DOI:	10.1093/humrep/dead002
Popis:	Double ovarian stimulation (DuoStim), initially only suggested for fertility preservation in cancer patients, is now increasingly also used in routine clinical IVF, especially in poor responders. The claimed rational for this is the alleged existence of multiple follicular waves in a single intermenstrual interval, allowing for retrieval of more oocytes in a single IVF cycle. This commentary argues that this expansion of purpose lacks rationale, evidence, and follow-up. Consequently, we suggest that, unless valid clinical indications have been established, DuoStim be only subject of controlled clinical trials with appropriate experimental consents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4263e0f99d0b4166f82b5ddaf65d6966 https://doi.org/10.1093/humrep/dead002 Zobrazit plný text záznamu