Heterotopic liver transplantation after biliary obstruction

Autor: Stanley Minkowitz, Karl E. Karlson, Jose Pangan, Alan S. Josephson, Leonard Popowitz, Peter K. Kottmeier, Marvin L. Gliedman
Rok vydání: 1967
Předmět:
Zdroj: Journal of Pediatric Surgery. 2:144-154
ISSN: 0022-3468
DOI: 10.1016/s0022-3468(67)80298-7
Popis: Summary An auxiliary liver transplant in a normal recipient could not be satisfactorily appraised, as to function, by changes in host liver function because the host liver masked graft disfunction. With high immunosuppressive regimens, graft survival, with only arterial inflow was limited to 1 month and 6 weeks after cessation of function the graft was absorbed completely in surviving animals. The dog, dingo, coyote, fox and pig were compared by karyotype immuno-electrophoresis and transplantation characteristics. The dingo, coyote and dog appear indistinguishable, while the fox with a different karyotype and the apparent same immunoelectrophoresis is quite close phylogenetically to the dog. The fox liver transplanted into a dog was comparable to homografts in function and survival in one third of the attempts. Porcine grafts transplanted into the dog rapidly ceased perfusing.
Databáze: OpenAIRE